Education
BA, MA, & PhD in Psychology (Behavioral Neuroscience) from The University of Mississippi
Teaching Interests
Biological Psychology, Psychopharmacology, Seminars on 1) preclinical animal models of psychological/psychiatric syndromes and 2) the role of gut biota on behavior.
Research Interests
- Utilization of preclinical models of anxiety & depression for better understanding the etiopathology of mood disorders and evaluation of novel anxiolytics and antidepressants
- Understanding the role of gut biota in the development of mood disorders
- Animal models of nociception and analgesia
- Dr White is accepting undergraduate research assistants. To inquire you can email him at whitesw@appstate.edu
Publications
Journal Articles
White, S.W., Callahan, H.M, Smith, S.J., Padilla, F.M. (2024). Fluoxetine attenuates the anxiolytic effects of the probiotic VSL#3 in a stress-vulnerable genetic line of aves in the chick social-separation stress test, a dual screening assay. Pharmacology, Biochemistry, & Behavior; Special Issue on Anxiety and Anxiolytics, 245, 173880. https://doi.org/10.1016/j.pbb.2024.173880
White, S. W., Squires, G. D., Smith, S. J., Wright, G. M., Sufka, K. J., Rimoldi, J. M., & Gadepalli, R. S. (2023). Anxiolytic-like effects of an mGluR 5 antagonist and a mGluR 2/3 agonist, and antidepressant-like effects of an mGluR 7 agonist in the chick social separation stress test, a dual-drug screening model of treatment-resistant depression. Pharmacology, Biochemistry, and Behavior, 227-228, 173588. https://doi.org/10.1016/j.pbb.2023.173588
B. Krembuszewski, E. Anderson-White, C. Henderson, S. White, and H. Langley (2023). Positive Psychology as a Protective Factor for Illicit Opioids in Individuals Receiving Methadone Treatment. Heroin Addiction and Related Clinical Problems. 25; 7-15.
Abdelazeem, A. H., Khan, S. I., White, S. W., Sufka, K. J., & McCurdy, C. R. (2015). Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential antiinflammatory/analgesic agents. Bioorganic & Medicinal Chemistry, 23(13), 3248–3259. https://doi.org/10.1016/j.bmc.2015.04.057
Sufka, K. J., & White, S. W. (2013). Identification of a treatment-resistant, ketamine-sensitive genetic line in the chick anxiety-depression model. Pharmacology, Biochemistry, and Behavior, 113, 63–67. https://doi.org/10.1016/j.pbb.2013.10.013
Lewellyn, K., Bialonska, D., Loria, M. J., White, S. W., Sufka, K. J., & Zjawiony, J. K. (2013). In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model. Bioorganic & Medicinal Chemistry, 21(22), 7083–7090. https://doi.org/10.1016/j.bmc.2013.09.011
Hymel, K. A., Salmeto, A. L., Loria, M. J., White, S. W., & Sufka, K. J. (2013). Strain vulnerability and resiliency in the chick anxiety-depression model. Physiology & Behavior, 120, 124–129. https://doi.org/10.1016/j.physbeh.2013.07.013
Loria, M. J., White, S. W., Robbins, S. A., Salmeto, A. L., Hymel, K. A., Murthy, S. N., Manda, P., & Sufka, K. J. (2013). Brain-derived neurotrophic factor response in vulnerable and resilient genetic lines in the chick anxiety-depression model. Behavioural Brain Research, 245, 29–33. https://doi.org/10.1016/j.bbr.2013.01.045
Book Chapters
White S.W., Sufka KJ (2016). Development and validation of pre-clinical models of treatment-resistant depression. Models of Treatment-Resistant Depression. Nova Science Publishers.
White S.W., Sufka KJ (2012) Chick anxiety-depression screening model. In A. Szallasi (Ed.), Methods in Pharmacology and Toxicology: TRP Channels in Drug Discovery, Vol. II. Springer/Humana Press, pp. 203-210.
Conference Posters and Presentations
Vanessa Villarreal & Stephen W. White (October 2024). Betanin, a phytochemical from the beetroot plant, produces antidepressant effects in the chick social-separation stress test. Society for Neuroscience, Chicago, IL.
Trinity L. Castro, Josue I. Cuero, Stephen W. White (November 2023). Evaluation of glutamatergic receptors as targets for anxiolytic and/or antidepressant effects in an avian model of treatment-resistant depression. Society for Neuroscience, Washington, D.C.
Stephen W. White, Haylie M. Callahan, Sequioa J. Smith (November 2023). Probiotics produce anxiolytic effects but not antidepressant effects in the chick social-separation stress test, a dual-drug screening model of treatment-resistant depression. Society for Neuroscience, Washington D.C.
Nathaniel Rodriguez, Stephen W. White (March 2023). Do probiotics produce anxiolytic effects by reducing plasma cortisol levels? Southwestern Psychological Association, Frisco, TX.
Same poster presented by students at Armadillo (Cognitive Psychology), Texas State University, October 2023.
Trinity L. Castro, Addison E. Kanke, Felicia M. Padilla, Stephen W. White. (March 2023). Assessment and reversal of cognitive bias in stress-vulnerable and stress-resilient genetic lines of aves. Southwestern Psychological Association, Frisco, TX.
Haylie M. Callahan, Sequioa J. Smith, Stephen W. White (March 2023). Oral Media: Probiotics produce anxiolytic effects in a stress-vulnerable genetic line of aves. Southwestern Psychological Association, Frisco, TX.
Sequioa J. Smith, Stephen W. White (March 2023). Oral Media: Evaluation of glutamatergic ligands in an avian model of treatment-resistant depression. Southwestern Psychological Association, Frisco, TX.
Stephen W. White, Gwendolyn D. Squires, Sequioa J. Smith, Gwendolyn M. Wright, Kenneth J. Sufka, John M. Rimoldi, Rama S. Gadepalli (November 2022). Evaluation of glutamatergic targets for anxiolytic and/or antidepressant effects in an avian model of treatment-resistant depression. Society for Neuroscience, San Diego, CA.
Gwendolyn M. Wright, Stephen W. White (April 2022). Evaluation of the mGluR 2/3 agonist LY404039 for potential anxiolytic effects in an avian model of anxiety and depression. Southwestern Psychological Association, Baton Rouge, LA.
